ISPAGHULA
Synonymous: Isapgol, Isabgol.
Which means of word (isapgol = ear of the pony).
Organic Source :
Isapgol contains of dried seeds of the plant (Plantago ovata ,P. psyllium, P.arenaria,P.amplexicaulis) Forskal, (Family : Plantaginaceae).
Chemical Constituents :
Isapgol husk comprises adhesive which is available in epidermis of the seed. Isapgol comprises of pentosan and aldobionic corrosive.
The hydrolysis items are xylose, arabinose, galacturonic corrosive and rhamnose.
Fixed oil and proteins are other Vital constituents of medication.
Compound Tests:
1. To dry seeds of Isapgol add one drop of Test arrangement of Chinese ink, adhesive shows straightforward, circularly widened fragements on dark foundation.
2. Being adhesive artificially, isapgol gives pink tone with ruthenium red.
3. To dry isapgol seeds add a drop of Thionine test arrangement, hang tight for 10 minutes, wash with liquor adhesive change violet-red.
Remedial Efficacy :
1) The seeds and husk are utilized as demulcent, diuretic, and emollient.
2) It is utilized for treating persistent obstruction, amoebic and bacillary loose bowels.
3) Its adhesive is utilized in tablet readiness
4) The squashed seeds are utilized as poultice for calming rheumatic torment.
5) It is utilized in duodenal ulcers and heaps.
✧･ﾟ: *✧･ﾟ:* Senna ✧･ﾟ: *✧･ﾟ:*
Equivalents
Cassia Folia senna, and Tinnevelles senna.
Natural Source :
Senna is dried leaflet of (Cassia angustifolia)
Family-Liguminoseae
Compound Constitutions
Senna contains basically 2 anthraquinone glycosides called as sennoside-A and-B (at least 2.5%) which represent its laxative property. rhein and aloe-emodin. In 1941 revealed segregation of translucent sennosides A and B. Substance Constituents Sennosides A and B are stereoisomers . They are dimeric glycosides with rhein dianthrone Like aglycone, for example 10,10 bis (9,10-dihydro-1-8-dihydroxy-9-oxoanthracane-3-carboxylic corrosive).
In sennoside B, the aglycone is in meso structure; and in sennoside A, it is dextro-rotatory. Laxative action of sennosides-A and B, accounts up to 40-60% movement of unrefined medication.
It is additionally revealed that sugar a piece of these glycosides has moving capacity for the aglycone up to internal organ and furthermore defensive activity so oxidation of aglycone to other exceptionally less dynamic anthraquinones is forestalled.
Senna leaf additionally contains other anthraquinone glycosides in little amount.
They are sennosides-C and D, rhein 8-glucoside, rhein 8-diglucoside, aloe-emodin, 8-glucoside, anthrone diglucoside, rhein, kaempferol, aloe-emodin, and isorhamnetin.
Senna likewise contains phytosterol, adhesive, sap, myricyl liquor, salicylic corrosive, chrysophanic corrosive, and calcium oxalate.
Compound tests:
1) Borntrager's test
It is utilized for reason for anthraquinones in senna leaves.
Medication is overflowed with weaken sulphuric corrosive, sifted and to filtrate, benzene or ether or chloroform is added then shaken well.
Natural layer is isolated to which NH3 is added gradually. Ammoniacal layer shows pink to red tone because of present of anthraquinone glycosides.
Remedial Efficacy :
1} It is predominantly utilized as a laxative.
It contains glycosides which get retained in the little intestinal waterway, and afterward its aglycone part gets isolated and at last discharges in the digestive organ (colon).
The delivered anthraquinones disturb and invigorate the colon to improve its peristaltic developments, in this way causing massive and delicate discharge of facces.
2} It is utilized as an energizer therapeutic .
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